Identifying heterogeneity of human adipose tissue

 

In studies in collaboration with the Tseng Lab, and with the generous support of the Chan-Zuckerberg Initiative (Seed Networks, component of the Human Cell Atlas), we are utilizing single-nucleus RNA sequencing and ATAC-sequencing to identify subpopulations of adipose tissue resident cells and their differences in states of insulin resistance and T2D.  Postdoc Arionas Efthymiou PhD is leading this effort in the lab, and was recently selected to deliver an oral presentation describing these data at the Copenhagen BAT Meeting "The heterogeneity and plasticity of adipose tissue" and at the American Diabetes Association Scientific Sessions in June 2022.

Summary Figure Efthymiou et al