Chang, Lin, Jifeng Zhang, Yu-Hua Tseng, Chang-Qing Xie, Jacob Ilany, Jens Brüning, Zhongcui Sun, et al. 2007. “Rad GTPase deficiency leads to cardiac hypertrophy”. Circulation 116 (25): 2976-83.
Abstract
BACKGROUND: Rad (Ras associated with diabetes) GTPase is the prototypic member of a subfamily of Ras-related small G proteins. The aim of the present study was to define whether Rad plays an important role in mediating cardiac hypertrophy.
METHODS AND RESULTS: We document for the first time that levels of Rad mRNA and protein were decreased significantly in human failing hearts (n=10) compared with normal hearts (n=3; P
Last updated on 03/08/2023